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GDF15 mediates the effects of metformin on body weight and energy balance
GDF15 mediates the effects of metformin on body weight and energy balance
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GDF15 mediates the effects of metformin on body weight and energy balance

Coll, Anthony P ; Chen, Michael ; Taskar, Pranali ; Rimmington, Debra ; Patel, Satish ; Tadross, John A ; Cimino, Irene ; Yang, Ming ; Welsh, Paul ; Virtue, Samuel ; Goldspink, Deborah A ; Miedzybrodzka, Emily L ; Konopka, Adam R ; Esponda, Raul Ruiz ; Huang, Jeffrey T-J ; Tung, Y C Loraine ; Rodriguez-Cuenca, Sergio ; Tomaz, Rute A ; Harding, Heather P ; Melvin, Audrey ; Yeo, Giles S H ; Preiss, David ; Vidal-Puig, Antonio ; Vallier, Ludovic ; Nair, K Sreekumaran ; Wareham, Nicholas J ; Ron, David ; Gribble, Fiona M ; Reimann, Frank ; Sattar, Naveed ; Savage, David B ; Allan, Bernard B ; O'Rahilly, Stephen

Nature (London), 2020-02, Vol.578 (7795), p.444-448 [Peer Reviewed Journal]

England: Nature Publishing Group

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2
The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15
The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15
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The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15

Kincaid, John W R ; Rimmington, Debra ; Tadross, John A ; Cimino, Irene ; Zvetkova, Ilona ; Kaser, Arthur ; Richards, Paul ; Patel, Satish ; O'Rahilly, Stephen ; Coll, Anthony P

Scientific reports, 2024-01, Vol.14 (1), p.1899-1899, Article 1899 [Peer Reviewed Journal]

England: Nature Publishing Group

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3
Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring
Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring
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Effects of maternal diet-induced obesity on metabolic disorders and age-associated miRNA expression in the liver of male mouse offspring

Mennitti, Laís Vales ; Carpenter, Asha A M ; Loche, Elena ; Pantaleão, Lucas C ; Fernandez-Twinn, Denise S ; Schoonejans, Josca M ; Blackmore, Heather L ; Ashmore, Thomas J ; Pisani, Luciana Pellegrini ; Tadross, John A ; Hargreaves, Iain ; Ozanne, Susan E

International Journal of Obesity, 2022-02, Vol.46 (2), p.269-278 [Peer Reviewed Journal]

England: Nature Publishing Group

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4
Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15
Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15
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Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15

Cimino, Irene ; Kim, Hanna ; Tung, Y C Loraine ; Pedersen, Kent ; Rimmington, Debra ; Tadross, John A ; Kohnke, Sara N ; Neves-Costa, Ana ; Barros, André ; Joaquim, Stephanie ; Bennett, Don ; Melvin, Audrey ; Lockhart, Samuel M ; Rostron, Anthony J ; Scott, Jonathan ; Liu, Hui ; Burling, Keith ; Barker, Peter ; Clatworthy, Menna R ; Lee, E-Chiang ; Simpson, A John ; Yeo, Giles S H ; Moita, Luís F ; Bence, Kendra K ; Jørgensen, Sebastian Beck ; Coll, Anthony P ; Breen, Danna M ; O'Rahilly, Stephen

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (27), p.1 [Peer Reviewed Journal]

United States: National Academy of Sciences

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5
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing
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A survey of the mouse hindbrain in the fed and fasted states using single-nucleus RNA sequencing

Dowsett, Georgina K.C. ; Lam, Brian Y.H. ; Tadross, John A. ; Cimino, Irene ; Rimmington, Debra ; Coll, Anthony P. ; Polex-Wolf, Joseph ; Knudsen, Lotte Bjerre ; Pyke, Charles ; Yeo, Giles S.H.

Molecular metabolism (Germany), 2021-11, Vol.53, p.101240-101240, Article 101240 [Peer Reviewed Journal]

Germany: Elsevier GmbH

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6
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
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Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice

Ramos-Pittol, Jose M ; Fernandes-Freitas, Isabel ; Milona, Alexandra ; Manchishi, Stephen M ; Rainbow, Kara ; Lam, Brian Y H ; Tadross, John A ; Beucher, Anthony ; Colledge, William H ; Cebola, Inês ; Murphy, Kevin G ; Miguel-Aliaga, Irene ; Yeo, Giles S H ; Dhillo, Waljit S ; Owen, Bryn M

Nature communications, 2023-05, Vol.14 (1), p.3076-10, Article 3076 [Peer Reviewed Journal]

England: Nature Publishing Group

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7
Identification of an Activating PDGFRA Deletion in a Novel Sinonasal Soft Tissue Neoplasm
Identification of an Activating PDGFRA Deletion in a Novel Sinonasal Soft Tissue Neoplasm
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Identification of an Activating PDGFRA Deletion in a Novel Sinonasal Soft Tissue Neoplasm

Watkins, James A. ; Hatcher, Helen ; Malhotra, Shalini ; Amen, Furrat ; Bruty, Jonathan ; Trotman, Jamie ; Tarpey, Patrick ; Tadross, John A.

Head & neck pathology (Totowa, N.J.), 2023-06, Vol.17 (2), p.576-580 [Peer Reviewed Journal]

New York: Springer US

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8
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
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Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

Patel, Satish ; Haider, Afreen ; Alvarez-Guaita, Anna ; Bidault, Guillaume ; El-Sayed Moustafa, Julia Sarah ; Guiu-Jurado, Esther ; Tadross, John A. ; Warner, James ; Harrison, James ; Virtue, Samuel ; Scurria, Fabio ; Zvetkova, Ilona ; Blüher, Matthias ; Small, Kerrin S. ; O’Rahilly, Stephen ; Savage, David B.

Molecular metabolism (Germany), 2022-11, Vol.65, p.101589-101589, Article 101589 [Peer Reviewed Journal]

Germany: Elsevier GmbH

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9
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice
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Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice

Lewis, Jo E. ; Woodward, Orla RM ; Nuzzaci, Danaé ; Smith, Christopher A. ; Adriaenssens, Alice E. ; Billing, Lawrence ; Brighton, Cheryl ; Phillips, Benjamin U. ; Tadross, John A. ; Kinston, Sarah J. ; Ciabatti, Ernesto ; Göttgens, Berthold ; Tripodi, Marco ; Hornigold, David ; Baker, David ; Gribble, Fiona M. ; Reimann, Frank

Molecular metabolism (Germany), 2022-12, Vol.66, p.101604-101604, Article 101604 [Peer Reviewed Journal]

Germany: Elsevier GmbH

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10
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake
The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake
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The vagus nerve mediates the physiological but not pharmacological effects of PYY3-36 on food intake

Alonso, Aldara Martin ; Cork, Simon C. ; Phuah, Phyllis ; Hansen, Benjamin ; Norton, Mariana ; Cheng, Sijing ; Xu, Xiang ; Suba, Kinga ; Ma, Yue ; Dowsett, Georgina KC ; Tadross, John A. ; Lam, Brian YH ; Yeo, Giles SH ; Herzog, Herbert ; Bloom, Stephen R. ; Arnold, Myrtha ; Distaso, Walter ; Murphy, Kevin G. ; Salem, Victoria

Molecular metabolism (Germany), 2024-03, Vol.81, p.101895-101895, Article 101895 [Peer Reviewed Journal]

Elsevier GmbH

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