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Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial
Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial
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Acalabrutinib with or without obinutuzumab versus chlorambucil and obinutuzmab for treatment-naive chronic lymphocytic leukaemia (ELEVATE TN): a randomised, controlled, phase 3 trial

Sharman, Jeff P ; Egyed, Miklos ; Jurczak, Wojciech ; Skarbnik, Alan ; Pagel, John M ; Flinn, Ian W ; Kamdar, Manali ; Munir, Talha ; Walewska, Renata ; Corbett, Gillian ; Fogliatto, Laura Maria ; Herishanu, Yair ; Banerji, Versha ; Coutre, Steven ; Follows, George ; Walker, Patricia ; Karlsson, Karin ; Ghia, Paolo ; Janssens, Ann ; Cymbalista, Florence ; Woyach, Jennifer A ; Salles, Gilles ; Wierda, William G ; Izumi, Raquel ; Munugalavadla, Veerendra ; Patel, Priti ; Wang, Min Hui ; Wong, Sofia ; Byrd, John C

The Lancet (British edition), 2020-04, Vol.395 (10232), p.1278 [Periódico revisado por pares]

England

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2
ASCEND: Phase III, Randomized Trial of Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia
ASCEND: Phase III, Randomized Trial of Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia
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ASCEND: Phase III, Randomized Trial of Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia

Ghia, Paolo ; Pluta, Andrzej ; Wach, Malgorzata ; Lysak, Daniel ; Kozak, Tomas ; Simkovic, Martin ; Kaplan, Polina ; Kraychok, Iryna ; Illes, Arpad ; de la Serna, Javier ; Dolan, Sean ; Campbell, Phillip ; Musuraca, Gerardo ; Jacob, Abraham ; Avery, Eric ; Lee, Jae Hoon ; Liang, Wei ; Patel, Priti ; Quah, Cheng ; Jurczak, Wojciech

Journal of clinical oncology, 2020-09, Vol.38 (25), p.2849-2861 [Periódico revisado por pares]

United States

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3
Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study
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Tazemetostat in advanced epithelioid sarcoma with loss of INI1/SMARCB1: an international, open-label, phase 2 basket study

Gounder, Mrinal ; Schöffski, Patrick ; Jones, Robin L ; Agulnik, Mark ; Cote, Gregory M ; Villalobos, Victor M ; Attia, Steven ; Chugh, Rashmi ; Chen, Tom Wei-Wu ; Jahan, Thierry ; Loggers, Elizabeth T ; Gupta, Abha ; Italiano, Antoine ; Demetri, George D ; Ratan, Ravin ; Davis, Lara E ; Mir, Olivier ; Dileo, Palma ; Van Tine, Brian A ; Pressey, Joseph G ; Lingaraj, Trupti ; Rajarethinam, Anand ; Sierra, Laura ; Agarwal, Shefali ; Stacchiotti, Silvia

The lancet oncology, 2020-11, Vol.21 (11), p.1423-1432 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study
Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study
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Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study

Italiano, Antoine ; Soria, Jean-Charles ; Toulmonde, Maud ; Michot, Jean-Marie ; Lucchesi, Carlo ; Varga, Andrea ; Coindre, Jean-Michel ; Blakemore, Stephen J ; Clawson, Alicia ; Suttle, Benjamin ; McDonald, Alice A ; Woodruff, Mark ; Ribich, Scott ; Hedrick, Eric ; Keilhack, Heike ; Thomson, Blythe ; Owa, Takashi ; Copeland, Robert A ; Ho, Peter T C ; Ribrag, Vincent

The lancet oncology, 2018-05, Vol.19 (5), p.649-659 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial
Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial
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Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial

Morschhauser, Franck ; Tilly, Hervé ; Chaidos, Aristeidis ; McKay, Pamela ; Phillips, Tycel ; Assouline, Sarit ; Batlevi, Connie Lee ; Campbell, Phillip ; Ribrag, Vincent ; Damaj, Gandhi Laurent ; Dickinson, Michael ; Jurczak, Wojciech ; Kazmierczak, Maciej ; Opat, Stephen ; Radford, John ; Schmitt, Anna ; Yang, Jay ; Whalen, Jennifer ; Agarwal, Shefali ; Adib, Deyaa ; Salles, Gilles

The lancet oncology, 2020-11, Vol.21 (11), p.1433-1442 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
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Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

Byrd, John C ; Harrington, Bonnie ; O’Brien, Susan ; Jones, Jeffrey A ; Schuh, Anna ; Devereux, Steve ; Chaves, Jorge ; Wierda, William G ; Awan, Farrukh T ; Brown, Jennifer R ; Hillmen, Peter ; Stephens, Deborah M ; Ghia, Paolo ; Barrientos, Jacqueline C ; Pagel, John M ; Woyach, Jennifer ; Johnson, Dave ; Huang, Jane ; Wang, Xiaolin ; Kaptein, Allard ; Lannutti, Brian J ; Covey, Todd ; Fardis, Maria ; McGreivy, Jesse ; Hamdy, Ahmed ; Rothbaum, Wayne ; Izumi, Raquel ; Diacovo, Thomas G ; Johnson, Amy J ; Furman, Richard R

The New England journal of medicine, 2016-01, Vol.374 (4), p.323-332 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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7
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol
Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol
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Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol

Attard, Gerhardt ; Murphy, Laura ; Clarke, Noel W ; Jones, Robert J ; Cook, Adrian ; Brawley, Chris ; Amos, Claire L ; Atako, Nafisah ; Chowdhury, Simon ; Russell, J Martin ; Gilson, Clare ; Rush, Hannah ; Bowen, Jo ; O'Sullivan, Joe M ; Birtle, Alison ; Gale, Joanna ; Srihari, Narayanan ; Tanguay, Jacob ; Gray, Emma ; Alzoueb, Mymoona ; Parikh, Omi ; Robinson, Angus ; Syndikus, Isabel ; Wylie, James ; Thalmann, George ; Dearnaley, David P ; Mason, Malcolm D ; Gilbert, Duncan ; Sydes, Matthew R ; Brown, Louise C ; Parmar, Mahesh K B ; Jones, Elin ; Hyde, Katherine ; Glen, Hilary ; Needleman, Sarah ; McGovern, Ursula ; Sheehan, Denise ; Paisey, Sangeeta ; Shaffer, Richard ; Beresford, Mark ; Malik, Zafar ; Zarkar, Anjali ; Porfiri, Emilio ; Brock, Sue ; Bahl, Amit ; Smith-Howell, Mike ; Woodward, Cathryn ; Phan, Mau-Don ; Mazhar, Danish ; Hamid, Abdel ; Ibrahim, Azman ; Muthukumar, Dakshinamoorthy ; Worlding, Jane ; Kagzi, Mohammed ; Pezaro, Carmel ; Keng-Koh, Pek ; McLaren, Duncan ; Gupta, Nishi ; Boussios, Stergios ; Taylor, Henry ; Perna, Carla ; Grant, Warren ; Sabharwal, Ami ; Hofmann, Uschi ; Dealey, Robert ; Brierly, Robert ; Capaldi, Lisa ; Vivekanandan, Sindu ; Tipples, Karen ; Afshar, Mehran ; Brulinski, Patryk ; Sangar, Vijay ; Peedell, Clive ; Mullassery, Viwod ; Protheroe, Andrew ; Tarver, Kathryn ; Gibbs, Stephanie ; Khan, Mohammad Muneeb ; Hingorani, Mohan ; Crabb, Simon ; Bhalla, Neeraj ; Logue, John ; Leaning, Darren ; Vengalil, Salil ; Ford, Daniel ; Walker, Georgina ; Shaheen, Ahmed ; Chan, Andrew ; Ahmed, Imtiaz ; Hilman, Serena ; Sayers, Ian ; Porter, Tim ; Joseph, Joji ; Rentsch, Cyrill ; Roggero, Enrico ; Beyer, Jörg ; Strebel, Raeto ; Engeler, Daniel ; John, Hubert ; Durr, Donat

The Lancet (British edition), 2022-01, Vol.399 (10323), p.447-460 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH
Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH
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Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH

Loomba, Rohit ; Noureddin, Mazen ; Kowdley, Kris V. ; Kohli, Anita ; Sheikh, Aasim ; Neff, Guy ; Bhandari, Bal Raj ; Gunn, Nadege ; Caldwell, Stephen H. ; Goodman, Zachary ; Wapinski, Ilan ; Resnick, Murray ; Beck, Andrew H. ; Ding, Dora ; Jia, Catherine ; Chuang, Jen‐Chieh ; Huss, Ryan S. ; Chung, Chuhan ; Subramanian, G. Mani ; Myers, Robert P. ; Patel, Keyur ; Borg, Brian B. ; Ghalib, Reem ; Kabler, Heidi ; Poulos, John ; Younes, Ziad ; Elkhashab, Magdy ; Hassanein, Tarek ; Iyer, Rajalakshmi ; Ruane, Peter ; Shiffman, Mitchell L. ; Strasser, Simone ; Wong, Vincent Wai‐Sun ; Alkhouri, Naim

Hepatology (Baltimore, Md.), 2021-02, Vol.73 (2), p.625-643 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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9
Oral Tecovirimat for the Treatment of Smallpox
Oral Tecovirimat for the Treatment of Smallpox
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Oral Tecovirimat for the Treatment of Smallpox

Grosenbach, Douglas W ; Honeychurch, Kady ; Rose, Eric A ; Chinsangaram, Jarasvech ; Frimm, Annie ; Maiti, Biswajit ; Lovejoy, Candace ; Meara, Ingrid ; Long, Paul ; Hruby, Dennis E

The New England journal of medicine, 2018-07, Vol.379 (1), p.44-53 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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10
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial
Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial
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Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial

Wang, Michael ; Rule, Simon ; Zinzani, Pier Luigi ; Goy, Andre ; Casasnovas, Olivier ; Smith, Stephen D ; Damaj, Gandhi ; Doorduijn, Jeanette ; Lamy, Thierry ; Morschhauser, Franck ; Panizo, Carlos ; Shah, Bijal ; Davies, Andrew ; Eek, Richard ; Dupuis, Jehan ; Jacobsen, Eric ; Kater, Arnon P ; Le Gouill, Steven ; Oberic, Lucie ; Robak, Taduesz ; Covey, Todd ; Dua, Richa ; Hamdy, Ahmed ; Huang, Xin ; Izumi, Raquel ; Patel, Priti ; Rothbaum, Wayne ; Slatter, J Greg ; Jurczak, Wojciech

The Lancet (British edition), 2018-02, Vol.391 (10121), p.659-667 [Periódico revisado por pares]

England: Elsevier Ltd

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