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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Bartek, Jiri ; Helleday, Thomas ; Sørensen, Claus Storgaard ; Hansen, Lasse Tengbjerg ; Dziegielewski, Jaroslaw ; Syljuåsen, Randi G ; Lundin, Cecilia

Nature cell biology, 2005-02, Vol.7 (2), p.195-201 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks
Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks
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Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks

Saleh-Gohari, Nasrollah ; Bryant, Helen E ; Schultz, Niklas ; Parker, Kayan M ; Cassel, Tobias N ; Helleday, Thomas

Molecular and Cellular Biology, 2005-08, Vol.25 (16), p.7158-7169 [Periódico revisado por pares]

United States: American Society for Microbiology

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3
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
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Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

Weinfeld, Michael ; Helleday, Thomas ; Lupski, James R ; Caldecott, Keith W ; El-Khamisy, Sherif F ; Johansson, Fredrik ; Saifi, Gulam M

Nature, 2005-03, Vol.434 (7029), p.108-113 [Periódico revisado por pares]

London: Nature Publishing

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4
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
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DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1

Ogitani, Yusuke ; Aida, Tetsuo ; Hagihara, Katsunobu ; Yamaguchi, Junko ; Ishii, Chiaki ; Harada, Naoya ; Soma, Masako ; Okamoto, Hiromi ; Oitate, Masataka ; Arakawa, Shingo ; Hirai, Takehiro ; Atsumi, Ryo ; Nakada, Takashi ; Hayakawa, Ichiro ; Abe, Yuki ; Agatsuma, Toshinori

Clinical cancer research, 2016-10, Vol.22 (20), p.5097-5108 [Periódico revisado por pares]

United States

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5
Supramolecular “Trojan Horse” for Nuclear Delivery of Dual Anticancer Drugs
Supramolecular “Trojan Horse” for Nuclear Delivery of Dual Anticancer Drugs
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Supramolecular “Trojan Horse” for Nuclear Delivery of Dual Anticancer Drugs

Cai, Yanbin ; Shen, Haosheng ; Zhan, Jie ; Lin, Mingliang ; Dai, Liuhan ; Ren, Chunhua ; Shi, Yang ; Liu, Jianfeng ; Gao, Jie ; Yang, Zhimou

Journal of the American Chemical Society, 2017-03, Vol.139 (8), p.2876-2879 [Periódico revisado por pares]

United States: American Chemical Society

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6
A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization
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A Novel HER3-Targeting Antibody-Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Hashimoto, Yuuri ; Koyama, Kumiko ; Kamai, Yasuki ; Hirotani, Kenji ; Ogitani, Yusuke ; Zembutsu, Akiko ; Abe, Manabu ; Kaneda, Yuki ; Maeda, Naoyuki ; Shiose, Yoshinobu ; Iguchi, Takuma ; Ishizaka, Tomomichi ; Karibe, Tsuyoshi ; Hayakawa, Ichiro ; Morita, Koji ; Nakada, Takashi ; Nomura, Taisei ; Wakita, Kenichi ; Kagari, Takashi ; Abe, Yuki ; Murakami, Masato ; Ueno, Suguru ; Agatsuma, Toshinori

Clinical cancer research, 2019-12, Vol.25 (23), p.7151-7161 [Periódico revisado por pares]

United States

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7
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

Arnaudeau, Catherine ; Lundin, Cecilia ; Helleday, Thomas

Journal of molecular biology, 2001-04, Vol.307 (5), p.1235-1245 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Trastuzumab Deruxtecan: First Approval
Trastuzumab Deruxtecan: First Approval
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Trastuzumab Deruxtecan: First Approval

Keam, Susan J.

Drugs (New York, N.Y.), 2020-04, Vol.80 (5), p.501-508 [Periódico revisado por pares]

Cham: Springer International Publishing

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9
Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer
Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer
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Tumor-penetrating peptide enhances transcytosis of silicasome-based chemotherapy for pancreatic cancer

Liu, Xiangsheng ; Lin, Paulina ; Perrett, Ian ; Lin, Joshua ; Liao, Yu-Pei ; Chang, Chong Hyun ; Jiang, Jinhong ; Wu, Nanping ; Donahue, Timothy ; Wainberg, Zev ; Nel, Andre E ; Meng, Huan

The Journal of clinical investigation, 2017-05, Vol.127 (5), p.2007-2018 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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10
Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics
Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics
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Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

García-González, Aurian P. ; Ritter, Ashlyn D. ; Shrestha, Shaleen ; Andersen, Erik C. ; Yilmaz, L. Safak ; Walhout, Albertha J.M.

Cell, 2017-04, Vol.169 (3), p.431-441.e8 [Periódico revisado por pares]

United States: Elsevier Inc

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