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DNA Topoisomerase Inhibitors: Trapping a DNA-Cleaving Machine in Motion
DNA Topoisomerase Inhibitors: Trapping a DNA-Cleaving Machine in Motion
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DNA Topoisomerase Inhibitors: Trapping a DNA-Cleaving Machine in Motion

Bax, Benjamin D. ; Murshudov, Garib ; Maxwell, Anthony ; Germe, Thomas

Journal of molecular biology, 2019-08, Vol.431 (18), p.3427-3449 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors
Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors
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Antibacterial activity of novel dual bacterial DNA type II topoisomerase inhibitors

D'Atanasio, Noemi ; Capezzone de Joannon, Alessandra ; Di Sante, Laura ; Mangano, Giorgina ; Ombrato, Rosella ; Vitiello, Marco ; Bartella, Cristina ; Magarò, Gabriele ; Prati, Federica ; Milanese, Claudio ; Vignaroli, Carla ; Di Giorgio, Francesco Paolo ; Tongiani, Serena Narayanasamy, Prabagaran

PloS one, 2020-02, Vol.15 (2), p.e0228509-e0228509 [Periódico revisado por pares]

United States: Public Library of Science

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3
Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis
Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis
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Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis

Wang, Zongqiang ; Forelli, Nicholas ; Hernandez, Yozen ; Ternei, Melinda ; Brady, Sean F

Nature communications, 2022-02, Vol.13 (1), p.842-842, Article 842 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint
Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint
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Roles of the C-terminal domains of topoisomerase IIα and topoisomerase IIβ in regulation of the decatenation checkpoint

Kozuki, Toshiyuki ; Chikamori, Kenichi ; Surleac, Marius D ; Micluta, Marius A ; Petrescu, Andrei J ; Norris, Eric J ; Elson, Paul ; Hoeltge, Gerald A ; Grabowski, Dale R ; Porter, Andrew C G ; Ganapathi, Ram N ; Ganapathi, Mahrukh K

Nucleic acids research, 2017-06, Vol.45 (10), p.5995-6010 [Periódico revisado por pares]

England: Oxford University Press

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5
Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells
Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells
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Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells

Islam, Mohammad Shahidul ; Park, Seojeong ; Song, Chanju ; Kadi, Adnan A. ; Kwon, Youngjoo ; Rahman, A.F.M. Motiur

European journal of medicinal chemistry, 2017-01, Vol.125, p.49-67 [Periódico revisado por pares]

France: Elsevier Masson SAS

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6
Alteration of Topoisomerase II–Alpha Gene in Human Breast Cancer: Association With Responsiveness to Anthracycline-Based Chemotherapy
Alteration of Topoisomerase II–Alpha Gene in Human Breast Cancer: Association With Responsiveness to Anthracycline-Based Chemotherapy
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Alteration of Topoisomerase II–Alpha Gene in Human Breast Cancer: Association With Responsiveness to Anthracycline-Based Chemotherapy

PRESS, Michael F ; SAUTER, Guido ; ROBERT, Nicholas ; CROWN, John ; BEE, Valerie ; TAUPIN, Henry ; FLOM, Kerry J ; TABAH-FISCH, Isabelle ; PAULETTI, Giovanni ; LINDSAY, Mary-Ann ; RIVA, Alessandro ; SLAMON, Dennis J ; BUYSE, Marc ; BERNSTEIN, Leslie ; GUZMAN, Roberta ; SANTIAGO, Angela ; VILLALOBOS, Ivonne E ; EIERMANN, Wolfgang ; PIENKOWSKI, Tadeusz ; MARTIN, Miguel

Journal of clinical oncology, 2011-03, Vol.29 (7), p.859-867 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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7
Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging
Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging
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Quantification of single-strand DNA lesions caused by the topoisomerase II poison etoposide using single DNA molecule imaging

Singh, Vandana ; Johansson, Pegah ; Ekedahl, Elina ; Lin, Yii-Lih ; Hammarsten, Ola ; Westerlund, Fredrik

Biochemical and biophysical research communications, 2022-02, Vol.594, p.57-62 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Topoisomerase poisoning by the flavonoid nevadensin triggers DNA damage and apoptosis in human colon carcinoma HT29 cells
Topoisomerase poisoning by the flavonoid nevadensin triggers DNA damage and apoptosis in human colon carcinoma HT29 cells
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Topoisomerase poisoning by the flavonoid nevadensin triggers DNA damage and apoptosis in human colon carcinoma HT29 cells

Müller, Lena ; Schütte, Larissa Rhonda Friederike ; Bücksteeg, David ; Alfke, Julian ; Uebel, Thomas ; Esselen, Melanie

Archives of toxicology, 2021-12, Vol.95 (12), p.3787-3802 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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9
Potent Antiviral Activity of Topoisomerase I and II Inhibitors against Kaposi's Sarcoma-Associated Herpesvirus
Potent Antiviral Activity of Topoisomerase I and II Inhibitors against Kaposi's Sarcoma-Associated Herpesvirus
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Potent Antiviral Activity of Topoisomerase I and II Inhibitors against Kaposi's Sarcoma-Associated Herpesvirus

González-Molleda, Lorenzo ; Wang, Yan ; Yuan, Yan

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.893-902 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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10
Pericentromeric Satellite III transcripts induce etoposide resistance
Pericentromeric Satellite III transcripts induce etoposide resistance
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Pericentromeric Satellite III transcripts induce etoposide resistance

Kanne, Julian ; Hussong, Michelle ; Isensee, Jörg ; Muñoz-López, Álvaro ; Wolffgramm, Jan ; Heß, Felix ; Grimm, Christina ; Bessonov, Sergey ; Meder, Lydia ; Wang, Jie ; Reinhardt, H Christian ; Odenthal, Margarete ; Hucho, Tim ; Büttner, Reinhard ; Summerer, Daniel ; Schweiger, Michal R

Cell death & disease, 2021-05, Vol.12 (6), p.530-15, Article 530 [Periódico revisado por pares]

England: Springer Nature B.V

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