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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
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Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Verbanck, Marie ; Chen, Chia-Yen ; Neale, Benjamin ; Do, Ron

Nature genetics, 2018-05, Vol.50 (5), p.693-698 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
Evaluating the potential role of pleiotropy in Mendelian randomization studies
Evaluating the potential role of pleiotropy in Mendelian randomization studies
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Evaluating the potential role of pleiotropy in Mendelian randomization studies

Hemani, Gibran ; Bowden, Jack ; Davey Smith, George

Human molecular genetics, 2018-08, Vol.27 (R2), p.R195-R208 [Periódico revisado por pares]

England: Oxford University Press

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3
Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function
Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function
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Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function

Shadrina, Alexandra S ; Zlobin, Alexander S ; Zaytseva, Olga O ; Klarić, Lucija ; Sharapov, Sodbo Z ; D Pakhomov, Eugene ; Perola, Marcus ; Esko, Tonu ; Hayward, Caroline ; Wilson, James F ; Lauc, Gordan ; Aulchenko, Yurii S ; Tsepilov, Yakov A

Human molecular genetics, 2021-06, Vol.30 (13), p.1259-1270 [Periódico revisado por pares]

England: Oxford University Press

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4
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways
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Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Duffy, David L ; Zhu, Gu ; Li, Xin ; Sanna, Marianna ; Iles, Mark M ; Jacobs, Leonie C ; Evans, David M ; Yazar, Seyhan ; Beesley, Jonathan ; Law, Matthew H ; Kraft, Peter ; Visconti, Alessia ; Taylor, John C ; Liu, Fan ; Wright, Margaret J ; Henders, Anjali K ; Bowdler, Lisa ; Glass, Dan ; Ikram, M Arfan ; Uitterlinden, André G ; Madden, Pamela A ; Heath, Andrew C ; Nelson, Elliot C ; Green, Adele C ; Chanock, Stephen ; Barrett, Jennifer H ; Brown, Matthew A ; Hayward, Nicholas K ; MacGregor, Stuart ; Sturm, Richard A ; Hewitt, Alex W ; Kayser, Manfred ; Hunter, David J ; Newton Bishop, Julia A ; Spector, Timothy D ; Montgomery, Grant W ; Mackey, David A ; Smith, George Davey ; Nijsten, Tamar E ; Bishop, D Timothy ; Bataille, Veronique ; Falchi, Mario ; Han, Jiali ; Martin, Nicholas G

Nature communications, 2018-11, Vol.9 (1), p.4774-10, Article 4774 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders
Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders
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Beyond the One Gene–One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders

Cerrone, Marina ; Remme, Carol Ann ; Tadros, Rafik ; Bezzina, Connie R ; Delmar, Mario

Circulation (New York, N.Y.), 2019-08, Vol.140 (7), p.595-610 [Periódico revisado por pares]

United States: by the American College of Cardiology Foundation and the American Heart Association, Inc

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6
Detection and interpretation of shared genetic influences on 42 human traits
Detection and interpretation of shared genetic influences on 42 human traits
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Detection and interpretation of shared genetic influences on 42 human traits

Pickrell, Joseph K ; Berisa, Tomaz ; Liu, Jimmy Z ; Ségurel, Laure ; Tung, Joyce Y ; Hinds, David A

Nature genetics, 2016-07, Vol.48 (7), p.709-717 [Periódico revisado por pares]

United States: Nature Publishing Group

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7
The many faces of pleiotropy
The many faces of pleiotropy
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The many faces of pleiotropy

Paaby, Annalise B ; Rockman, Matthew V

Trends in genetics, 2013-02, Vol.29 (2), p.66-73 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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8
Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective
Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective
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Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective

Ong, Jue‐Sheng ; MacGregor, Stuart

Genetic epidemiology, 2019-09, Vol.43 (6), p.609-616 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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9
Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects
Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects
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Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects

Burgess, Stephen ; Thompson, Simon G

American journal of epidemiology, 2015-02, Vol.181 (4), p.251-260 [Periódico revisado por pares]

United States: Oxford University Press

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10
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens
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Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

Kiryluk, Krzysztof ; Li, Yifu ; Scolari, Francesco ; Sanna-Cherchi, Simone ; Choi, Murim ; Verbitsky, Miguel ; Fasel, David ; Lata, Sneh ; Prakash, Sindhuri ; Shapiro, Samantha ; Fischman, Clara ; Snyder, Holly J ; Appel, Gerald ; Izzi, Claudia ; Viola, Battista Fabio ; Dallera, Nadia ; Del Vecchio, Lucia ; Barlassina, Cristina ; Salvi, Erika ; Bertinetto, Francesca Eleonora ; Amoroso, Antonio ; Savoldi, Silvana ; Rocchietti, Marcella ; Amore, Alessandro ; Peruzzi, Licia ; Coppo, Rosanna ; Salvadori, Maurizio ; Ravani, Pietro ; Magistroni, Riccardo ; Ghiggeri, Gian Marco ; Caridi, Gianluca ; Bodria, Monica ; Lugani, Francesca ; Allegri, Landino ; Delsante, Marco ; Maiorana, Mariarosa ; Magnano, Andrea ; Frasca, Giovanni ; Boer, Emanuela ; Boscutti, Giuliano ; Ponticelli, Claudio ; Mignani, Renzo ; Marcantoni, Carmelita ; Di Landro, Domenico ; Santoro, Domenico ; Pani, Antonello ; Polci, Rosaria ; Feriozzi, Sandro ; Chicca, Silvana ; Galliani, Marco ; Gigante, Maddalena ; Gesualdo, Loreto ; Zamboli, Pasquale ; Battaglia, Giovanni Giorgio ; Garozzo, Maurizio ; Maixnerová, Dita ; Tesar, Vladimir ; Eitner, Frank ; Rauen, Thomas ; Floege, Jürgen ; Kovacs, Tibor ; Nagy, Judit ; Mucha, Krzysztof ; Pączek, Leszek ; Zaniew, Marcin ; Mizerska-Wasiak, Małgorzata ; Roszkowska-Blaim, Maria ; Pawlaczyk, Krzysztof ; Gale, Daniel ; Barratt, Jonathan ; Thibaudin, Lise ; Berthoux, Francois ; Canaud, Guillaume ; Boland, Anne ; Metzger, Marie ; Panzer, Ulf ; Suzuki, Hitoshi ; Goto, Shin ; Narita, Ichiei ; Caliskan, Yasar ; Xie, Jingyuan ; Hou, Ping ; Chen, Nan ; Zhang, Hong ; Wyatt, Robert J ; Novak, Jan ; Julian, Bruce A ; Feehally, John ; Stengel, Benedicte ; Cusi, Daniele ; Lifton, Richard P ; Gharavi, Ali G

Nature genetics, 2014-11, Vol.46 (11), p.1187-1196 [Periódico revisado por pares]

United States: Nature Publishing Group

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