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1 |
Material Type: Artigo
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Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cellsHendel, Ayal ; Bak, Rasmus O ; Clark, Joseph T ; Kennedy, Andrew B ; Ryan, Daniel E ; Roy, Subhadeep ; Steinfeld, Israel ; Lunstad, Benjamin D ; Kaiser, Robert J ; Wilkens, Alec B ; Bacchetta, Rosa ; Tsalenko, Anya ; Dellinger, Douglas ; Bruhn, Laurakay ; Porteus, Matthew HNature biotechnology, 2015-09, Vol.33 (9), p.985-989 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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An enhanced CRISPR repressor for targeted mammalian gene regulationYeo, Nan Cher ; Chavez, Alejandro ; Lance-Byrne, Alissa ; Chan, Yingleong ; Menn, David ; Milanova, Denitsa ; Kuo, Chih-Chung ; Guo, Xiaoge ; Sharma, Sumana ; Tung, Angela ; Cecchi, Ryan J ; Tuttle, Marcelle ; Pradhan, Swechchha ; Lim, Elaine T ; Davidsohn, Noah ; Ebrahimkhani, Mo R ; Collins, James J ; Lewis, Nathan E ; Kiani, Samira ; Church, George MNature methods, 2018-08, Vol.15 (8), p.611-616 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNAFonfara, Ines ; Richter, Hagen ; Bratovič, Majda ; Le Rhun, Anaïs ; Charpentier, EmmanuelleNature (London), 2016-04, Vol.532 (7600), p.517-521 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12aSwarts, Daan C. ; Jinek, MartinMolecular cell, 2019-02, Vol.73 (3), p.589-600.e4 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12aSwarts, Daan C. ; van der Oost, John ; Jinek, MartinMolecular cell, 2017-04, Vol.66 (2), p.221-233.e4 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13aLiu, Liang ; Li, Xueyan ; Ma, Jun ; Li, Zongqiang ; You, Lilan ; Wang, Jiuyu ; Wang, Min ; Zhang, Xinzheng ; Wang, YanliCell, 2017-08, Vol.170 (4), p.714-726.e10 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory ProteinYan, Winston X. ; Chong, Shaorong ; Zhang, Huaibin ; Makarova, Kira S. ; Koonin, Eugene V. ; Cheng, David R. ; Scott, David A.Molecular cell, 2018-04, Vol.70 (2), p.327-339.e5 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Target preference of Type III-A CRISPR-Cas complexes at the transcription bubbleLiu, Tina Y ; Liu, Jun-Jie ; Aditham, Abhishek J ; Nogales, Eva ; Doudna, Jennifer ANature communications, 2019-07, Vol.10 (1), p.3001-13, Article 3001 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas SystemsO'Connell, Mitchell R.Journal of molecular biology, 2019-01, Vol.431 (1), p.66-87 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
10 |
Material Type: Artigo
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Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13dZhang, Cheng ; Konermann, Silvana ; Brideau, Nicholas J. ; Lotfy, Peter ; Wu, Xuebing ; Novick, Scott J. ; Strutzenberg, Timothy ; Griffin, Patrick R. ; Hsu, Patrick D. ; Lyumkis, DmitryCell, 2018-09, Vol.175 (1), p.212-223.e17 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |