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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Zimmermann, Michal ; Murina, Olga ; Reijns, Martin A M ; Agathanggelou, Angelo ; Challis, Rachel ; Tarnauskaitė, Žygimantė ; Muir, Morwenna ; Fluteau, Adeline ; Aregger, Michael ; McEwan, Andrea ; Yuan, Wei ; Clarke, Matthew ; Lambros, Maryou B ; Paneesha, Shankara ; Moss, Paul ; Chandrashekhar, Megha ; Angers, Stephane ; Moffat, Jason ; Brunton, Valerie G ; Hart, Traver ; de Bono, Johann ; Stankovic, Tatjana ; Jackson, Andrew P ; Durocher, Daniel

Nature (London), 2018-07, Vol.559 (7713), p.285-289 [Periódico revisado por pares]

England: Nature Publishing Group

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2
GADD45A binds R-loops and recruits TET1 to CpG island promoters
GADD45A binds R-loops and recruits TET1 to CpG island promoters
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GADD45A binds R-loops and recruits TET1 to CpG island promoters

Arab, Khelifa ; Karaulanov, Emil ; Musheev, Michael ; Trnka, Philipp ; Schäfer, Andrea ; Grummt, Ingrid ; Niehrs, Christof

Nature genetics, 2019-02, Vol.51 (2), p.217-223 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability
RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability
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RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability

Wahba, Lamia ; Amon, Jeremy D. ; Koshland, Douglas ; Vuica-Ross, Milena

Molecular cell, 2011-12, Vol.44 (6), p.978-988 [Periódico revisado por pares]

United States: Elsevier Inc

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4
BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment
BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment
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BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment

D'Alessandro, Giuseppina ; Whelan, Donna Rose ; Howard, Sean Michael ; Vitelli, Valerio ; Renaudin, Xavier ; Adamowicz, Marek ; Iannelli, Fabio ; Jones-Weinert, Corey Winston ; Lee, MiYoung ; Matti, Valentina ; Lee, Wei Ting C ; Morten, Michael John ; Venkitaraman, Ashok Raraakrishnan ; Cejka, Petr ; Rothenberg, Eli ; d'Adda di Fagagna, Fabrizio

Nature communications, 2018-12, Vol.9 (1), p.5376-17, Article 5376 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response
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Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

Mackenzie, Karen J ; Carroll, Paula ; Lettice, Laura ; Tarnauskaitė, Žygimantė ; Reddy, Kaalak ; Dix, Flora ; Revuelta, Ailsa ; Abbondati, Erika ; Rigby, Rachel E ; Rabe, Björn ; Kilanowski, Fiona ; Grimes, Graeme ; Fluteau, Adeline ; Devenney, Paul S ; Hill, Robert E ; Reijns, Martin AM ; Jackson, Andrew P

The EMBO journal, 2016-04, Vol.35 (8), p.831-844 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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6
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
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Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy

Bartsch, Kareen ; Knittler, Katharina ; Borowski, Christopher ; Rudnik, Sönke ; Damme, Markus ; Aden, Konrad ; Spehlmann, Martina E ; Frey, Norbert ; Saftig, Paul ; Chalaris, Athena ; Rabe, Björn

Human molecular genetics, 2017-10, Vol.26 (20), p.3960-3972 [Periódico revisado por pares]

England

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7
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
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Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

Nguyen, Hai Dang ; Yadav, Tribhuwan ; Giri, Sumanprava ; Saez, Borja ; Graubert, Timothy A. ; Zou, Lee

Molecular cell, 2017-03, Vol.65 (5), p.832-847.e4 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair
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Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

Ohle, Corina ; Tesorero, Rafael ; Schermann, Géza ; Dobrev, Nikolay ; Sinning, Irmgard ; Fischer, Tamás

Cell, 2016-11, Vol.167 (4), p.1001-1013.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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9
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops
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FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

Silva, Bruno ; Pentz, Richard ; Figueira, Ana Margarida ; Arora, Rajika ; Lee, Yong Woo ; Hodson, Charlotte ; Wischnewski, Harry ; Deans, Andrew J ; Azzalin, Claus M

Nature communications, 2019-05, Vol.10 (1), p.2253-2253, Article 2253 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Comparisons of Ribonuclease HI Homologs and Mutants Uncover a Multistate Model for Substrate Recognition
Comparisons of Ribonuclease HI Homologs and Mutants Uncover a Multistate Model for Substrate Recognition
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Comparisons of Ribonuclease HI Homologs and Mutants Uncover a Multistate Model for Substrate Recognition

Martin, James A ; Palmer, Arthur G

Journal of the American Chemical Society, 2022-03, Vol.144 (12), p.5342-5349 [Periódico revisado por pares]

United States: American Chemical Society

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