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Material Type: Artigo
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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cellsDev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen PNature cell biology, 2018-08, Vol.20 (8), p.954-965 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Telomeres cooperate with the nuclear envelope to maintain genome stabilityRai, Rekha ; Sodeinde, Tori ; Boston, Ava ; Chang, SandyBioEssays, 2024-02, Vol.46 (2), p.e2300184-n/a [Periódico revisado por pares]United States: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor SensitivityGupta, Rajat ; Somyajit, Kumar ; Narita, Takeo ; Maskey, Elina ; Stanlie, Andre ; Kremer, Magdalena ; Typas, Dimitris ; Lammers, Michael ; Mailand, Niels ; Nussenzweig, Andre ; Lukas, Jiri ; Choudhary, ChunaramCell, 2018-05, Vol.173 (4), p.972-988.e23 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complexHu, Chunyi ; Rai, Rekha ; Huang, Chenhui ; Broton, Cayla ; Long, Juanjuan ; Xu, Ying ; Xue, Jing ; Lei, Ming ; Chang, Sandy ; Chen, YongCell research, 2017-12, Vol.27 (12), p.1485-1502 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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POT1 loss-of-function variants predispose to familial melanomaRobles-Espinoza, Carla Daniela ; Harland, Mark ; Ramsay, Andrew J ; Aoude, Lauren G ; Quesada, Víctor ; Ding, Zhihao ; Pooley, Karen A ; Pritchard, Antonia L ; Tiffen, Jessamy C ; Petljak, Mia ; Palmer, Jane M ; Symmons, Judith ; Johansson, Peter ; Stark, Mitchell S ; Gartside, Michael G ; Snowden, Helen ; Montgomery, Grant W ; Martin, Nicholas G ; Liu, Jimmy Z ; Choi, Jiyeon ; Makowski, Matthew ; Brown, Kevin M ; Dunning, Alison M ; Keane, Thomas M ; López-Otín, Carlos ; Gruis, Nelleke A ; Hayward, Nicholas K ; Bishop, D Timothy ; Newton-Bishop, Julia A ; Adams, David JNature genetics, 2014-05, Vol.46 (5), p.478-481 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structural biology of telomeres and telomeraseSmith, Eric M. ; Pendlebury, Devon F. ; Nandakumar, JayakrishnanCellular and molecular life sciences : CMLS, 2020-01, Vol.77 (1), p.61-79 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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Material Type: Artigo
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TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome EndsZhong, Franklin L. ; Batista, Luis F.Z. ; Freund, Adam ; Pech, Matthew F. ; Venteicher, Andrew S. ; Artandi, Steven E.Cell, 2012-08, Vol.150 (3), p.481-494 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityNANDAKUMAR, Jayakrishnan ; BELL, Caitlin F ; WEIDENFELD, Ina ; ZAUG, Arthur J ; LEINWAND, Leslie A ; CECH, Thomas RNature (London), 2012-12, Vol.492 (7428), p.285-289 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
9 |
Material Type: Artigo
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CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycleSarek, Grzegorz ; Kotsantis, Panagiotis ; Ruis, Phil ; Van Ly, David ; Margalef, Pol ; Borel, Valerie ; Zheng, Xiao-Feng ; Flynn, Helen R ; Snijders, Ambrosius P ; Chowdhury, Dipanjan ; Cesare, Anthony J ; Boulton, Simon JNature (London), 2019-11, Vol.575 (7783), p.523-527 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at TelomeresRodriguez, Raphaël ; Müller, Sebastian ; Yeoman, Justin A ; Trentesaux, Chantal ; Riou, Jean-François ; Balasubramanian, ShankarJournal of the American Chemical Society, 2008-11, Vol.130 (47), p.15758-15759 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |