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Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties
Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties
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Chalcogenium-AZT Derivatives: A Plausible Strategy To Tackle The RT-Inhibitors-Related Oxidative Stress While Maintaining Their Anti- HIV Properties

Sarturi, Joelma M ; Dornelles, Luciano ; Segatto, Natalia V ; Collares, Tiago ; Seixas, Fabiana K ; Piccoli, Bruna Candia ; da Silva, Fernanda D'Avila ; Omage, Folorunsho Bright ; da Rocha, João Batista Teixeira ; Balaguez, Renata A ; Alves, Diego ; Lenardão, Eder J ; Lopes, Eric F ; Kula-Pacurar, Anna ; Pyrc, Krzysztof ; Sancineto, Luca ; Rodrigues, Oscar E D

Current medicinal chemistry, 2023-01, Vol.30 (21), p.2449-2462 [Periódico revisado por pares]

United Arab Emirates: Bentham Science Publishers

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Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity
Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity
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Arginine-259 of UGT2B7 Confers UDP-Sugar Selectivity

Nair, Pramod C ; Chau, Nuy ; McKinnon, Ross A ; Miners, John O

Molecular pharmacology, 2020-12, Vol.98 (6), p.710-718 [Periódico revisado por pares]

United States

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3
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs
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TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs

Huang, Shar-yin N ; Murai, Junko ; Dalla Rosa, Ilaria ; Dexheimer, Thomas S ; Naumova, Alena ; Gmeiner, William H ; Pommier, Yves

Nucleic acids research, 2013-09, Vol.41 (16), p.7793-7803 [Periódico revisado por pares]

England: Oxford University Press

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4
Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3
Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3
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Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3

Minuesa, Gerard ; Volk, Christopher ; Molina-Arcas, Míriam ; Gorboulev, Valentin ; Erkizia, Itziar ; Arndt, Petra ; Clotet, Bonaventura ; Pastor-Anglada, Marçal ; Koepsell, Hermann ; Martinez-Picado, Javier

The Journal of pharmacology and experimental therapeutics, 2009-04, Vol.329 (1), p.252-261 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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5
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity
A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity
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A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity

Hernandez-Sanchez, Wilnelly ; Huang, Wei ; Plucinsky, Brian ; Garcia-Vazquez, Nelson ; Robinson, Nathaniel J ; Schiemann, William P ; Berdis, Anthony J ; Skordalakes, Emmanuel ; Taylor, Derek J Smogorzewska, Agata

PLoS biology, 2019-04, Vol.17 (4), p.e3000204 [Periódico revisado por pares]

United States: Public Library of Science

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6
Brain Uptake of a Zidovudine Prodrug after Nasal Administration of Solid Lipid Microparticles
Brain Uptake of a Zidovudine Prodrug after Nasal Administration of Solid Lipid Microparticles
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Brain Uptake of a Zidovudine Prodrug after Nasal Administration of Solid Lipid Microparticles

Dalpiaz, Alessandro ; Ferraro, Luca ; Perrone, Daniela ; Leo, Eliana ; Iannuccelli, Valentina ; Pavan, Barbara ; Paganetto, Guglielmo ; Beggiato, Sarah ; Scalia, Santo

Molecular pharmaceutics, 2014-05, Vol.11 (5), p.1550-1561 [Periódico revisado por pares]

United States: American Chemical Society

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7
Selenothymidine protects against biochemical and behavioral alterations induced by ICV-STZ model of dementia in mice
Selenothymidine protects against biochemical and behavioral alterations induced by ICV-STZ model of dementia in mice
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Selenothymidine protects against biochemical and behavioral alterations induced by ICV-STZ model of dementia in mice

Thomé, Gustavo Roberto ; Oliveira, Vitor Antunes ; Chitolina Schetinger, Maria Rosa ; Saraiva, Rogério Aquino ; Souza, Diego ; Dorneles Rodrigues, Oscar Endrigo ; Teixeira Rocha, João Batista ; Ineu, Rafael Porto ; Pereira, Maria Ester

Chemico-biological interactions, 2018-10, Vol.294, p.135-143 [Periódico revisado por pares]

Ireland: Elsevier B.V

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8
Recent progress in prodrug design strategies based on generally applicable modifications
Recent progress in prodrug design strategies based on generally applicable modifications
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Recent progress in prodrug design strategies based on generally applicable modifications

Hamada, Yoshio

Bioorganic & medicinal chemistry letters, 2017-04, Vol.27 (8), p.1627-1632 [Periódico revisado por pares]

England: Elsevier Ltd

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9
In Vitro Drug Metabolism Using Liver Microsomes
In Vitro Drug Metabolism Using Liver Microsomes
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In Vitro Drug Metabolism Using Liver Microsomes

Knights, Kathleen M. ; Stresser, David M. ; Miners, John O. ; Crespi, Charles L.

Current Protocols in Pharmacology, 2016-09, Vol.74 (1), p.7.8.1-7.8.24

United States

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10
Binding of Inhibitory Fatty Acids Is Responsible for the Enhancement of UDP-Glucuronosyltransferase 2B7 Activity by Albumin: Implications for in Vitro-in Vivo Extrapolation
Binding of Inhibitory Fatty Acids Is Responsible for the Enhancement of UDP-Glucuronosyltransferase 2B7 Activity by Albumin: Implications for in Vitro-in Vivo Extrapolation
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Binding of Inhibitory Fatty Acids Is Responsible for the Enhancement of UDP-Glucuronosyltransferase 2B7 Activity by Albumin: Implications for in Vitro-in Vivo Extrapolation

Rowland, Andrew ; Gaganis, Paraskevi ; Elliot, David J ; Mackenzie, Peter I ; Knights, Kathleen M ; Miners, John O

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.137-147 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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