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Mutation as a Toxicological Endpoint for Regulatory Decision‐Making
Mutation as a Toxicological Endpoint for Regulatory Decision‐Making
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Mutation as a Toxicological Endpoint for Regulatory Decision‐Making

Heflich, Robert H. ; Johnson, George E. ; Zeller, Andreas ; Marchetti, Francesco ; Douglas, George R. ; Witt, Kristine L. ; Gollapudi, B. Bhaskar ; White, Paul A.

Environmental and molecular mutagenesis, 2020-01, Vol.61 (1), p.34-41 [Peer Reviewed Journal]

Hoboken, USA: John Wiley & Sons, Inc

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2
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing

Wang, Yiying ; Mittelstaedt, Roberta A. ; Wynne, Rebecca ; Chen, Ying ; Cao, Xuefei ; Muskhelishvili, Levan ; Davis, Kelly ; Robison, Timothy W. ; Sun, Wei ; Schmidt, Elizabeth K. ; Smith, Thomas H. ; Norgaard, Zachary K. ; Valentine, Charles C. ; Yaplee, Jeffry ; Williams, Lindsey N. ; Salk, Jesse J. ; Heflich, Robert H.

Environmental and molecular mutagenesis, 2021-06, Vol.62 (5), p.306-318 [Peer Reviewed Journal]

Hoboken, USA: John Wiley & Sons, Inc

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3
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies
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A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies

Corton, J Christopher ; Mitchell, Constance A ; Auerbach, Scott ; Bushel, Pierre ; Ellinger-Ziegelbauer, Heidrun ; Escobar, Patricia A ; Froetschl, Roland ; Harrill, Alison H ; Johnson, Kamin ; Klaunig, James E ; Pandiri, Arun R ; Podtelezhnikov, Alexei A ; Rager, Julia E ; Tanis, Keith Q ; van der Laan, Jan Willem ; Vespa, Alisa ; Yauk, Carole L ; Pettit, Syril D ; Sistare, Frank D

Toxicological sciences, 2022-06, Vol.188 (1), p.4-16 [Peer Reviewed Journal]

United States: Oxford University Press

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4
Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing
Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing
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Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing

Valentine, Charles C. ; Young, Robert R. ; Fielden, Mark R. ; Kulkarni, Rohan ; Williams, Lindsey N. ; Li, Tan ; Minocherhomji, Sheroy ; Salk, Jesse J.

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (52), p.33414-33425 [Peer Reviewed Journal]

United States: National Academy of Sciences

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5
Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations
Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations
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Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations

LeBlanc, Danielle P M ; Meier, Matthew ; Lo, Fang Yin ; Schmidt, Elizabeth ; Valentine, 3rd, Charles ; Williams, Andrew ; Salk, Jesse J ; Yauk, Carole L ; Marchetti, Francesco

BMC genomics, 2022-07, Vol.23 (1), p.542-15, Article 542 [Peer Reviewed Journal]

England: BioMed Central

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6
Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride
Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride
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Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride

Dodge, Annette E. ; LeBlanc, Danielle P. M. ; Zhou, Gu ; Williams, Andrew ; Meier, Matthew J. ; Van, Phu ; Lo, Fang Yin ; Valentine III, Charles C. ; Salk, Jesse J. ; Yauk, Carole L. ; Marchetti, Francesco

Archives of toxicology, 2023-08, Vol.97 (8), p.2245-2259 [Peer Reviewed Journal]

Berlin/Heidelberg: Springer Berlin Heidelberg

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7
Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques
Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques
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Prediction and validation of hematopoietic stem and progenitor cell off-target editing in transplanted rhesus macaques

AlJanahi, Aisha A. ; Lazzarotto, Cicera R. ; Chen, Shirley ; Shin, Tae-Hoon ; Cordes, Stefan ; Fan, Xing ; Jabara, Isabel ; Zhou, Yifan ; Young, David J. ; Lee, Byung-Chul ; Yu, Kyung-Rok ; Li, Yuesheng ; Toms, Bradley ; Tunc, Ilker ; Hong, So Gun ; Truitt, Lauren L. ; Klermund, Julia ; Andrieux, Geoffroy ; Kim, Miriam Y. ; Cathomen, Toni ; Gill, Saar ; Tsai, Shengdar Q. ; Dunbar, Cynthia E.

Molecular therapy, 2022-01, Vol.30 (1), p.209-222 [Peer Reviewed Journal]

United States: Elsevier Inc

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8
Single-strand specific nuclease enhances accuracy of error-corrected sequencing and improves rare mutation-detection sensitivity
Single-strand specific nuclease enhances accuracy of error-corrected sequencing and improves rare mutation-detection sensitivity
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Single-strand specific nuclease enhances accuracy of error-corrected sequencing and improves rare mutation-detection sensitivity

Otsubo, Yuki ; Matsumura, Shoji ; Ikeda, Naohiro ; Yamane, Masayuki

Archives of toxicology, 2022-01, Vol.96 (1), p.377-386 [Peer Reviewed Journal]

Berlin/Heidelberg: Springer Berlin Heidelberg

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9
Sequencing-Based Measurable Residual Disease Testing in Acute Myeloid Leukemia
Sequencing-Based Measurable Residual Disease Testing in Acute Myeloid Leukemia
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Sequencing-Based Measurable Residual Disease Testing in Acute Myeloid Leukemia

Yoest, Jennifer M ; Shirai, Cara Lunn ; Duncavage, Eric J

Frontiers in cell and developmental biology, 2020-05, Vol.8, p.249-249 [Peer Reviewed Journal]

Switzerland: Frontiers Research Foundation

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10
Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring
Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring
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Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring

Crowgey, Erin L ; Mahajan, Nitin ; Wong, Wing Hing ; Gopalakrishnapillai, Anilkumar ; Barwe, Sonali P ; Kolb, E Anders ; Druley, Todd E

BMC medical genomics, 2020-03, Vol.13 (1), p.32-32, Article 32 [Peer Reviewed Journal]

England: BioMed Central Ltd

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